Aspirin & Fertility

Aspirin,  is a widely used medication with various medical properties. It belongs to the class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs). Aspirin is available over-the-counter and is commonly used to relieve pain, reduce inflammation, and lower fever.

Aspirin has been considered as a potential component of fertility treatment in specific situations, although its role remains a subject of debate and ongoing research.

Here are some key points from existing evidence

Recurrent Pregnancy Loss (RPL): Some studies suggest that aspirin may be beneficial for women who have experienced recurrent miscarriages. The rationale is that aspirin’s anti-inflammatory and antiplatelet effects might improve blood flow to the uterus, enhance placental development, and reduce the risk of blood clot formation that could lead to pregnancy loss.

Antiphospholipid Syndrome (APS): In cases of APS, a condition where the body’s immune system mistakenly attacks certain proteins in the blood, aspirin may be used in combination with other medications, such as heparin, to prevent blood clots and promote successful pregnancy outcomes.

In vitro fertilization (IVF): Some studies have explored the use of aspirin in IVF cycles to potentially improve embryo implantation rates. The proposed mechanism is that aspirin might enhance blood flow to the uterus and promote a more favorable uterine environment for embryo implantation.

Thin Endometrial Lining: For women with a thin endometrial lining, aspirin’s potential ability to improve blood flow to the uterine lining might be considered to aid in increasing the thickness and receptivity of the endometrium.

In summary

It is crucial to emphasise that the use of aspirin in fertility treatment is not universally recommended, and it should not be used indiscriminately. Aspirin can have side effects, particularly gastrointestinal irritation and bleeding, and its use should be based on an individualised assessment of each patient’s medical history, risk factors, and specific fertility issues.

The decision to use aspirin as part of your fertility treatment should be a well-informed, evidence-based decision, taking into account the potential risks and benefits for your unique circumstances. As such the use of aspirin in fertility treatment should always be done under the guidance of a fertility specialist