Clexane & Fertility

Clexane, also known as enoxaparin, is a brand name for low molecular weight heparin (LMWH), an anticoagulant medication. Clexane is used routinely in medicine to stop blood clots e.g deep vein thrombosis and pulmonary embolism. In fertility treatment, Clexane is sometimes prescribed after recurrent miscarriage and implantation failure.

Potential uses of Clexane in Fertility Treatment

Recurrent Pregnancy Loss (RPL): RPL, characterized by two or more consecutive pregnancy losses before 20 weeks of gestation, may be associated with underlying blood clotting disorders, such as antiphospholipid syndrome (APS). Clexane, along with low-dose aspirin, is often prescribed to women with APS or other clotting disorders to help reduce the risk of blood clots and improve the chances of a successful pregnancy.

Assisted Reproductive Technologies (ART): In some cases, fertility specialists may consider using Clexane during in vitro fertilization (IVF) treatment for selected patients. The rationale behind this is that Clexane’s anticoagulant properties might improve blood flow to the uterus and the developing embryo, potentially enhancing implantation and pregnancy success rates.

Thin Endometrial Lining: Clexane, as an LMWH, may be considered in cases of thin endometrial lining, which can impact embryo implantation. By promoting better blood flow to the endometrium, Clexane could help improve the thickness and receptivity of the uterine lining, increasing the likelihood of successful embryo implantation.

In summary

Clexane, may have a role in certain fertility treatment scenarios, particularly in cases involving recurrent pregnancy loss, thin endometrial lining, or specific ART protocols. However, its use should be carefully considered by your fertility treating team to ensure it is appropriate for your specific situation and that its benefits outweigh any potential risks.