Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone produced primarily in the adrenal glands, reproductive organs, and brain.
There is some evidence suggesting that DHEA supplementation may have a positive impact on fertility treatment outcomes, particularly in specific groups of women. However, it’s important to note that the evidence is not yet conclusive, and more research is needed to fully understand its effectiveness.
Diminished Ovarian Reserve: DHEA has been studied in women with diminished ovarian reserve, which refers to a decreased quantity and quality of eggs in the ovaries. Some studies suggest that DHEA supplementation may improve ovarian function and increase the number of eggs retrieved during in vitro fertilization (IVF) cycles in women with diminished ovarian reserve.
Advanced Maternal Age: Women over the age of 35 are at higher risk of experiencing age-related decline in fertility. Some research indicates that DHEA supplementation might be beneficial for improving pregnancy rates in this group of women.
Improvement in Egg Quality: DHEA has been suggested to potentially enhance egg quality, which could lead to better embryo development and implantation during fertility treatments.
Potential Anti-Inflammatory Effects: DHEA might have anti-inflammatory properties, which could be beneficial for women with certain inflammatory conditions that may affect fertility.
Varied Dosages and Duration: Studies have used different dosages and durations of DHEA supplementation, which makes it challenging to determine the optimal regimen for fertility treatment.
It’s important to approach the above findings with caution. The evidence for DHEA as a fertility treatment adjuvant is still evolving, and not all studies have shown consistent benefits. Additionally, DHEA supplementation might not be suitable for all women, especially those with specific medical conditions or hormonal imbalances.
As with any fertility treatment or supplementation, it’s crucial for women to discuss DHEA with their healthcare provider. Our fertility specialists can assess individual factors, including medical history, ovarian reserve, and overall health, to determine if DHEA supplementation may be appropriate and safe.