In Vitro Fertilisation (IVF) Clinic Perth

Welcome to Oasis Fertility Centre, an approachable and empathetic IVF clinic located in Perth, where advanced technology is offered with affordability and personalised care for your fertility journey. Our team of experienced doctors, embryologists, nurses, and administrative staff is dedicated to providing high-quality, comprehensive support tailored to your fertility journey. Nestled in a tranquil and supportive environment, our centre prioritises your well-being by offering access to a network of specialised practitioners, including psychologists, counselors, acupuncturists, and naturopaths.

With patient convenience in mind, Oasis proudly offers In Vitro Fertilisation services at our main centre, situated on the picturesque South Perth foreshore. Our brand new facility boasts a custom-built, state-of-the-art laboratory equipped with cutting-edge technology for IVF and a wide range of additional fertility treatments. Additionally, our satellite clinic in Warwick caters to those residing north of the river, ensuring consultations and in-cycle tracking procedures can be conducted closer to home.

Experience the difference at Oasis Fertility Centre, your trusted partner on you journey through IVF in Perth.

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What is IVF?

In Vitro Fertilisation (IVF) describes a type of Assisted Reproductive Technology whereby collected eggs, and a prepared sperm sample are added together in a dish and cultured in the laboratory. The goal of IVF is to have a sperm successfully reach and penetrate each mature egg to hopefully lead to fertilisation and subsequent embryo development.

The process of IVF essentially recreates the environment of the fallopian tube, in a laboratory setting. Unlike natural conception where usually only one egg is ovulated each month, IVF allows multiple eggs to be collected at once. This increased number of eggs leads to a higher chance of having a good quality embryo develop, which in turn helps reduce the time to achieving pregnancy. Furthermore, the fresh or frozen semen sample is prepared and washed before it is introduced into the dish containing the eggs. Through this process, most of the immotile sperm and other debris are removed so that only the best quality, motile sperm remains. Based on the sperm preparation, the Embryologist calculates the exact volume of sperm to add to the eggs to yield the greatest possible fertilisation outcome. The eggs and sperm are left together overnight, where nature takes over as the sperm swim in pursuit of fertilising the eggs. The following day, an Embryologist assesses each egg for signs of fertilisation, which indicates the DNA from the egg and the sperm have come together.

Who is suitable for IVF?

IVF is the recommended treatment option for couples who are experiencing female factor, or unexplained, infertility. If there is evidence of male factor infertility through an abnormal semen analysis, then ICSI insemination may be a more suitable treatment option.

IVF is best suited to couples who may have been trying to conceive naturally or through Intrauterine Insemination (IUI), without any luck. The Oasis Specialist will consider male and female medical history, conception history, and investigate any underlying factors which may be contributing to infertility to assess whether a couple is a good candidate for IVF.

IVF can also be beneficial for couples who may not be ready to start a family right away, but who are looking to preserve their fertility. Embryos can be created using IVF and frozen for use at a later date. These ‘freeze all’ cycles are often recommended to couples who may be undergoing unrelated treatment, or who require surgery prior to having an embryo transfer.

What happens after an IVF insemination?

After an IVF insemination, the inseminated eggs are placed into our incubators overnight to allow the sperm time to reach the eggs for fertilisation to occur. The following day, the eggs are assessed for maturity and fertilisation and moved into our Time-Lapse Incubators for continuous observation. At Oasis, the couple will receive a call from their Embryologist the day after egg collection to confirm their fertilisation result. The Embryologist will call with further embryo updates every second day thereafter. The developing embryos are given 5-6 days to grow until they are assessed for transfer or freezing.

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Risks of IVF include:

Multiple births. IVF increases the risk of multiple births if more than one embryo is transferred to your uterus. A pregnancy with multiple fetuses carries a higher risk of early labor and low birth weight than pregnancy with a single fetus does.
Premature delivery and low birth weight. Research suggests that IVF slightly increases the risk that the baby will be born early or with a low birth weight.
Ovarian hyperstimulation syndrome. Use of injectable fertility drugs, such as human chorionic gonadotrophin (HCG), to induce ovulation can cause ovarian hyperstimulation syndrome, in which your ovaries become swollen and painful.
Symptoms typically last a week and include mild abdominal pain, bloating, nausea, vomiting and diarrhea. If you become pregnant, however, your symptoms might last several weeks. Rarely ( 1-2%), it’s possible to develop a more severe form of ovarian hyperstimulation syndrome that can also cause rapid weight gain and shortness of breath.
Miscarriage. The rate of miscarriage for women who conceive using IVF with fresh embryos is similar to that of women who conceive naturally — about 15% to 20% — but the rate increases with maternal age.
Egg-retrieval procedure complications. Use of an aspirating needle to collect eggs could possibly cause bleeding, infection or damage to the bowel, bladder or a blood vessel. Risks are also associated with sedation and general anesthesia, if used.
Ectopic pregnancy. About 2% to 5% of women who use IVF will have an ectopic pregnancy — when the fertilised egg implants outside the uterus, usually in a fallopian tube. The fertilised egg can’t survive outside the uterus, and there’s no way to continue the pregnancy.
Birth defects. The age of the mother is the primary risk factor in the development of birth defects, no matter how the child is conceived. More research is needed to determine whether babies conceived using IVF might be at increased risk of certain birth defects.
Cancer. Although some early studies suggested there may be a link between certain medications used to stimulate egg growth and the development of a specific type of ovarian tumor, more-recent studies do not support these findings. There does not appear to be a significantly increased risk of breast, endometrial, cervical or ovarian cancer after IVF.
Stress. Use of IVF can be financially, physically and emotionally draining. Support from counselors, family and friends can help you and your partner through the ups and downs of infertility treatment.

Before beginning a cycle of IVF, consider important questions, including:

How many embryos will be transferred? The number of embryos transferred is typically based on age and number of eggs retrieved. Since the rate of implantation is lower for older women, more embryos are usually transferred — except for women using donor eggs or genetically tested embryos.
What will you do with any extra embryos? Extra embryos can be frozen and stored for future use for several years. Not all embryos will survive the freezing and thawing process, although most will. Having frozen embryos can make future cycles of IVF less expensive and less invasive. Or, you might be able to donate unused frozen embryos to another couple or a research facility. You might also choose to discard unused embryos.

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The 5 Steps of IVF

IVF involves several steps — ovarian stimulation, egg retrieval, sperm retrieval, fertilisation and embryo transfer. One cycle of IVF can take about two to three weeks. More than one cycle may be needed.

Step 1: Ovarian stimulation and monitoring:

The start of an IVF cycle begins by using Follicular stimulating hormones to stimulate the ovaries to produce multiple eggs — rather than the single egg that typically develops each month. Multiple eggs are needed because some eggs won’t fertilise or develop normally after fertilisation.

Several different medications may be used, such as:

Medications for ovarian stimulation. To stimulate your ovaries, you might receive an injectable medication containing a follicle-stimulating hormone (FSH), a combination of FSH and luteinising hormone(LH). These medications stimulate more than one egg to develop at a time.
Medications for oocyte maturation( trigger). When the follicles are ready for egg retrieval — generally after eight to 14 days — you will take human chorionic gonadotrophin (HCG) or ( decapaptyle) to help the eggs mature.
Medications to prevent premature ovulation. These medications prevent your body from releasing the developing eggs too soon.
Medications to prepare the lining of your uterus. On the day of egg retrieval ( after egg retrieval) you will be recommended that you begin taking progesterone supplements to make the lining of your uterus more receptive to implantation.

Typically, you’ll need 8-14 days of ovarian stimulation before your eggs are ready for retrieval. To determine when the eggs are ready for collection, you may have:

Vaginal ultrasound: to monitor follicular development. Usually when leading follicles are reaching 18mm or above, you are ready for trigger.
Blood tests, to measure your response to ovarian stimulation medications — estrogen levels typically increase as follicles develop, and progesterone levels remain low until after ovulation

Sometimes IVF cycles need to be cancelled before egg retrieval for one of these reasons:

Inadequate number of follicles developing
Premature ovulation
Too many follicles developing, creating a risk of ovarian hyperstimulation syndrome
Other medical issues

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Step 2: Egg retrieval

This is done in tandem with step 3. Egg retrieval can be done in your doctor’s office or a clinic 34 to 36 hours after the final injection and before ovulation.

During egg retrieval, you’ll be sedated and given pain medication.
Transvaginal ultrasound aspiration is the usual retrieval method. Then a thin needle is inserted into an ultrasound guide to go through the vagina and into the follicles to retrieve the eggs.
The eggs are removed from the follicles through a needle connected to a suction device. Multiple eggs can be removed in about 15-20 minutes.
After egg retrieval, you may experience cramping and feelings of fullness or pressure.
Mature eggs are placed in a culture medium which contains necessary nutrients for eggs and incubated. Eggs that appear healthy and mature will be mixed with sperm to attempt to create embryos. However, not all eggs may be successfully fertilised.

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Step 3: Sperm retrieval

This is done in tandem with step 2. If you’re using your partner’s sperm, a semen sample needs to be provided at clinic the morning of egg retrieval. Typically, the semen sample is collected through masturbation.

The other sources of sperm is surgically collected sperm (from your partner) and donor sperm.

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Step 4: Fertilisation

Fertilisation can be attempted using two common methods:

Conventional insemination. During conventional insemination, healthy sperm and mature eggs are mixed and incubated overnight.
Intracytoplasmic sperm injection (ICSI). In ICSI, a single healthy sperm is injected directly into each mature egg. ICSI is often used when semen quality or number is a problem or if fertilisation attempts during prior IVF cycles failed. Click here to find out more about ICSI.

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Step 5: Embryo transfer

Blastocyst
Embryo transfer is done at clinic and usually takes place two to five days after egg retrieval.

The procedure is usually painless, although you might experience mild cramping. Sometime you may request mild sedation.
The doctor will insert a long, thin, flexible tube called a catheter into your vagina, through your cervix and into your uterus.
A syringe containing one or more embryos suspended in a small amount of fluid is attached to the end of the catheter.
Using the syringe, the doctor places the embryo or embryos into your uterus.

If successful, an embryo will implant in the lining of your uterus about six to 10 days after egg retrieval.

After the procedure
After the embryo transfer, you can resume your usual daily activities. However, your ovaries may still be enlarged. Consider avoiding vigorous activity, which could cause discomfort.

Typical side effects include:

Passing a small amount of clear or bloody fluid shortly after the procedure — due to the swabbing of the cervix before the embryo transfer
Breast tenderness due to high estrogen levels
Mild bloating
Mild cramping
Constipation

If you develop moderate or severe pain after the embryo transfer, contact your doctor. He or she will evaluate you for complications such as infection, twisting of an ovary (ovarian torsion) and severe ovarian hyperstimulation syndrome.

Results

About 12 days to two weeks after egg retrieval, your doctor will test a sample of your blood to detect whether you’re pregnant.

If you’re pregnant, your doctor will refer you to an obstetrician or other pregnancy specialist for prenatal care.
If you’re not pregnant, you’ll stop taking progesterone and likely get your period within a week. If you don’t get your period or you have unusual bleeding, contact your doctor. If you’re interested in attempting another cycle of in vitro fertilisation (IVF), your doctor might suggest steps you can take to improve your chances of getting pregnant through IVF.

The chances of giving birth to a healthy baby after using IVF depend on various factors, including:

Maternal age. The younger you are, the more likely you are to get pregnant and give birth to a healthy baby using your own eggs during IVF.
Embryo status. Transfer of embryos that are more developed is associated with higher pregnancy rates compared with less-developed embryos (day two or three). However, not all embryos survive the development process. Talk with your doctor or other care provider about your specific situation.
Reproductive history. Women who’ve previously given birth are more likely to be able to get pregnant using IVF than are women who’ve never given birth. Success rates are lower for women who’ve previously used IVF multiple times but didn’t get pregnant.
Cause of infertility. Having a normal supply of eggs increases your chances of being able to get pregnant using IVF. Women who have severe endometriosis are less likely to be able to get pregnant using IVF than are women who have unexplained infertility.
Lifestyle factors. Women who smoke typically have fewer eggs retrieved during IVF and may miscarry more often. Smoking can lower a woman’s chance of success using IVF by 50%. Obesity can decrease your chances of getting pregnant and having a baby. Use of alcohol, recreational drugs, excessive caffeine and certain medications also can be harmful.

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