Culture media are solutions that are used to grow your embryos in the laboratory. SAGE 1-Step™ GM-CSF is the first one-step culture medium to contain the Granulocyte-Macrophage Colony-Stimulating Factor cytokine. GM-CSF is naturally produced by the female reproductive tract and levels peak with conception and implantation. It is thought that GM-CSF:

• Helps the embryo communicate with the uterus to facilitate implantation
• Regulates the maternal immune response to the introduced embryo
• Promotes embryo development
• Protects the embryos from cell stress